منابع مشابه
Airway mucus.
Hypersecretion of mucus is a cardinal sign of airways inflammation. Normally, secretion of mucus is designed to protect the respiratory portion of the lung from injury, but in disease its chronic overproduction in large airways (bronchi) and its appearance in small conducting airways (bronchioles) may be detrimental. Its relevance to patient discomfort and infection is generally accepted, but i...
متن کاملAirway mucus function and dysfunction.
From the Cardiovascular Research Institute and Department of Medicine, University of California, San Francisco, San Francisco (J.V.F.); and the Department of Pulmonary Medicine, University of Texas M.D. Anderson Cancer Center, Houston (B.F.D.). Address reprint requests to Dr. Dickey at the M.D. Anderson Cancer Center, P.O. Box 301402, 1515 Holcombe Blvd., Houston, TX, 77030-4009, or at bdickey@...
متن کاملMechanical insufflation-exsufflation for airway mucus clearance.
Cough is an important component of airway clearance, particularly in individuals with intrinsic pulmonary disease, weakness of respiratory muscles, or central nervous system disease that impairs breathing. The use of assisted cough to enhance airway clearance in individuals with neuromuscular disease is essential to produce and maintain peak cough flow above a minimum and thereby avoid retained...
متن کاملMucoactive agents for airway mucus hypersecretory diseases.
Airway mucus hypersecretion is a feature of a number of severe respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF). However, each disease has a different airway inflammatory response, with consequent, and presumably linked, mucus hypersecretory phenotype. Thus, it is possible that optimal treatment of the mucus hypersecretory element of...
متن کاملAirway mucosa: secretory cells, mucus and mucin genes.
The airway mucosa is lined by a continuous epithelium comprised of multiple cell phenotypes, several of which are secretory. Secretions produced by these cells mix with a variety of macromolecules, ions and water to form a respiratory tract fluid that protects the more distal airways and alveoli from injury and infection. The present article highlights the structure of the mucosa, particularly ...
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ژورنال
عنوان ژورنال: American Journal of Respiratory Cell and Molecular Biology
سال: 2006
ISSN: 1044-1549,1535-4989
DOI: 10.1165/rcmb.2005-0436sf